Rowell's syndrome

Rowell's syndrome is a rare and controversial autoimmune condition characterized by the coexistence of erythema multiforme-like lesions with lupus erythematosus (LE). The syndrome was first described by N. Rowell et al. in 1963.

Symptoms and Signs[edit | edit source]

The main symptoms of Rowell's syndrome include:

Erythema multiforme-like lesions
Positive antinuclear antibodies (ANA)
Positive rheumatoid factor (RF)
Speckled pattern of ANA
Sensitivity to light (photosensitivity)
Chilblains

Diagnosis[edit | edit source]

The diagnosis of Rowell's syndrome is based on the presence of lupus erythematosus (either systemic, discoid, or subacute), erythema multiforme-like lesions, and at least one of the immunological criteria (positive ANA, positive RF, or speckled pattern of ANA).

Treatment[edit | edit source]

Treatment of Rowell's syndrome is similar to that of lupus erythematosus and includes corticosteroids, antimalarial drugs, and immunosuppressive agents.

Prognosis[edit | edit source]

The prognosis of Rowell's syndrome is generally good, with most patients responding well to treatment. However, the condition can recur, and long-term follow-up is necessary.

References[edit | edit source]

Rowell's syndrome Resources
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