Rowell's syndrome
Rowell's syndrome is a rare and controversial autoimmune condition characterized by the coexistence of erythema multiforme-like lesions with lupus erythematosus (LE). The syndrome was first described by N. Rowell et al. in 1963.
Symptoms and Signs[edit | edit source]
The main symptoms of Rowell's syndrome include:
- Erythema multiforme-like lesions
- Positive antinuclear antibodies (ANA)
- Positive rheumatoid factor (RF)
- Speckled pattern of ANA
- Sensitivity to light (photosensitivity)
- Chilblains
Diagnosis[edit | edit source]
The diagnosis of Rowell's syndrome is based on the presence of lupus erythematosus (either systemic, discoid, or subacute), erythema multiforme-like lesions, and at least one of the immunological criteria (positive ANA, positive RF, or speckled pattern of ANA).
Treatment[edit | edit source]
Treatment of Rowell's syndrome is similar to that of lupus erythematosus and includes corticosteroids, antimalarial drugs, and immunosuppressive agents.
Prognosis[edit | edit source]
The prognosis of Rowell's syndrome is generally good, with most patients responding well to treatment. However, the condition can recur, and long-term follow-up is necessary.
See also[edit | edit source]
References[edit | edit source]
Rowell's syndrome Resources | |
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Contributors: Prab R. Tumpati, MD