Rutin

Rutin is a bioflavonoid and a type of flavonoid glycoside that is found in various plants, including buckwheat, rue, and the Japanese pagoda tree. It is also known as rutoside, quercetin-3-O-rutinoside, and sophorin. Rutin is known for its potential health benefits and is used in various dietary supplements and pharmaceuticals.

Chemical Structure and Properties

Rutin is a glycoside comprising the flavonol quercetin and the disaccharide rutinose. Its chemical formula is C27H30O16, and it has a molecular weight of 610.52 g/mol. Rutin is a yellow crystalline substance that is soluble in water and ethanol.

Sources

Rutin is naturally found in several plants, including:

• Buckwheat (Fagopyrum esculentum)
• Rue (Ruta graveolens)
• Japanese pagoda tree (Sophora japonica)
• Eucalyptus (Eucalyptus spp.)
• Citrus fruits

Health Benefits

Rutin is believed to have various health benefits, including:

• Antioxidant properties: Rutin helps in neutralizing free radicals and reducing oxidative stress.
• Anti-inflammatory effects: It may help in reducing inflammation and associated symptoms.
• Vascular health: Rutin is known to strengthen blood vessels and improve circulation, potentially reducing the risk of varicose veins and hemorrhoids.
• Anticancer potential: Some studies suggest that rutin may have properties that inhibit the growth of certain cancer cells.

Uses

Rutin is used in various forms, including:

• Dietary supplements: Available in capsules, tablets, and powders.
• Topical applications: Used in creams and ointments for its potential skin benefits.
• Pharmaceuticals: Included in medications for its vascular benefits.

Mechanism of Action

Rutin exerts its effects through several mechanisms, including:

• Scavenging free radicals and reducing oxidative stress.
• Inhibiting enzymes involved in inflammation.
• Strengthening capillary walls and improving vascular function.

Safety and Side Effects

Rutin is generally considered safe when consumed in moderate amounts. However, excessive intake may lead to side effects such as:

• Gastrointestinal discomfort
• Allergic reactions

See Also

• Flavonoid
• Quercetin
• Antioxidant
• Dietary supplement