S32212
S32212 is a novel antidepressant and anxiolytic drug used in the treatment of various types of mood disorders and anxiety disorders. It was developed by Servier Laboratories, a French pharmaceutical company, and is currently under clinical trials.
Pharmacology[edit | edit source]
S32212 acts as an inverse agonist at the 5-HT2C receptor, and to a lesser extent at the 5-HT2A receptor and 5-HT2B receptor. It also has high affinity for alpha-2 adrenergic receptors and dopamine D2 receptors. The drug's mechanism of action is thought to involve the enhancement of dopamine and norepinephrine neurotransmission in the prefrontal cortex, which is believed to contribute to its antidepressant and anxiolytic effects.
Clinical Trials[edit | edit source]
S32212 has undergone Phase I and II clinical trials for the treatment of major depressive disorder and generalized anxiety disorder. The results of these trials have shown that the drug is well-tolerated and has a favorable safety profile. Further studies are needed to confirm its efficacy and safety in a larger population.
Potential Uses[edit | edit source]
In addition to its potential use in the treatment of mood and anxiety disorders, S32212 may also have potential in the treatment of schizophrenia and Parkinson's disease. This is due to its ability to enhance dopamine and norepinephrine neurotransmission in the prefrontal cortex, which is often impaired in these conditions.
See Also[edit | edit source]
References[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
