SDZ SER-082
SDZ SER-082 is a serotonin receptor antagonist that is used in scientific research. It is a selective antagonist for the 5-HT1A receptor, which is a subtype of the serotonin receptor. SDZ SER-082 is used to study the role of 5-HT1A receptors in various physiological processes and diseases, including anxiety, depression, and schizophrenia.
Pharmacology[edit | edit source]
SDZ SER-082 acts by binding to 5-HT1A receptors and blocking their activation by serotonin. This inhibits the effects of serotonin, a neurotransmitter that plays a key role in mood regulation, sleep, and other functions. By selectively blocking 5-HT1A receptors, SDZ SER-082 allows researchers to study the specific role of these receptors in the body.
Uses in Research[edit | edit source]
SDZ SER-082 is primarily used in preclinical research. It has been used in studies investigating the role of 5-HT1A receptors in anxiety and depression, as well as in the pathophysiology of schizophrenia. In addition, it has been used to study the effects of 5-HT1A receptor antagonism on sleep and circadian rhythms.
Side Effects[edit | edit source]
As a research compound, SDZ SER-082 is not intended for human consumption, and its side effects in humans are not well-studied. However, in animal studies, it has been shown to cause side effects such as decreased locomotor activity and increased body temperature.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
