SF-268

SF-268 is a specific type of cell line used in biomedical research. It is a human glioblastoma cell line, which is a type of brain tumor. SF-268 cells are often used in cancer research to study the biology of glioblastomas and to test potential therapeutic strategies.

History

The SF-268 cell line was established in 1977 from a 76-year-old female patient with glioblastoma. The cells were derived from a tumor that was surgically removed from the patient's brain. Since then, SF-268 cells have been used in numerous research studies worldwide.

Characteristics

SF-268 cells are adherent cells, meaning they attach to the surface of the culture dish. They have a high mitotic index, which means they divide rapidly. This makes them useful for studying the processes of cell division and cell cycle regulation.

Applications

SF-268 cells are used in a variety of research applications. They are often used to study the genetics and molecular biology of glioblastomas. They are also used to test potential chemotherapeutic agents and other treatments for glioblastoma.

Limitations

While SF-268 cells are a valuable tool in cancer research, they do have some limitations. For example, they may not fully represent the complexity and heterogeneity of glioblastomas in patients. Therefore, findings from SF-268 cell studies must be validated in other models and in clinical trials.

See also

• Cell culture
• Cancer research
• Glioblastoma

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