SKF-38,393

From WikiMD's Wellnesspedia

SKF-38,393 is a synthetic compound of the benzazepine chemical class which acts as a selective D1 receptor full agonist. It is used in scientific research to study the D1 receptor's role in the brain.

Chemistry[edit | edit source]

SKF-38,393 is a member of the benzazepine class of compounds. Benzazepines are seven-membered heterocyclic compounds containing a nitrogen atom. They are known for their diverse range of biological activities, including acting as ligands for various receptors in the brain.

Pharmacology[edit | edit source]

SKF-38,393 acts as a full agonist at the D1 receptor, one of the five subtypes of the dopamine receptor. Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). The D1 receptor in particular is linked to the intracellular accumulation of cyclic adenosine monophosphate (cAMP).

Research Use[edit | edit source]

In scientific research, SKF-38,393 is used to study the role of the D1 receptor in various processes in the brain, including learning and memory, drug addiction, and the effects of Parkinson's disease. It has been used in both in vitro and in vivo studies.

See Also[edit | edit source]

Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Prab R. Tumpati, MD