SLC22A18
SLC22A18 is a gene that in humans is encoded by the SLC22A18 protein. It is also known as the solute carrier family 22 member 18 gene. This gene is located on chromosome 11p15.5, a region which is associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, and lung cancer.
Function[edit | edit source]
The SLC22A18 gene is part of the solute carrier family, which is a large group of membrane transport proteins that facilitate the movement of a wide variety of solutes across biological membranes. The SLC22A18 protein is thought to play a role in the transport of small molecules.
Clinical significance[edit | edit source]
Mutations in the SLC22A18 gene have been associated with several types of cancer. The gene is located in a region of chromosome 11 that is often deleted in neuroblastoma, lung cancer, and breast cancer. This has led to the suggestion that SLC22A18 may function as a tumor suppressor gene.
Research[edit | edit source]
Research into the SLC22A18 gene and its associated protein is ongoing. Current areas of investigation include the role of the gene in cancer development and progression, and its potential as a target for new cancer therapies.
See also[edit | edit source]
References[edit | edit source]
Translate: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD