SLC22A25

SLC22A25 is a gene that in humans encodes a protein known as solute carrier family 22 member 25. This protein is a part of the solute carrier family, which is a large group of membrane transport proteins that facilitate the movement of a wide variety of solutes across biological membranes.

Function

The SLC22A25 gene is part of the solute carrier family, a group of proteins that are responsible for the transport of a wide variety of solutes across biological membranes. The specific function of the SLC22A25 protein is not yet fully understood, but it is believed to play a role in the transport of small molecules and ions across the cell membrane.

Structure

The SLC22A25 gene is located on the long (q) arm of chromosome 11 at position 23.3. The gene spans approximately 50 kilobases and consists of 10 exons. The encoded protein is predicted to have 12 transmembrane domains, which is typical for members of the solute carrier family.

Clinical significance

While the exact role of SLC22A25 in human health and disease is not yet fully understood, mutations in this gene have been associated with various health conditions. For example, a study published in 2018 found a potential association between variants in the SLC22A25 gene and susceptibility to type 2 diabetes.

See also

• Solute carrier family
• Chromosome 11
• Type 2 diabetes