SPANXN1
SPANXN1 is a gene that is part of the SPANX gene family. The SPANX gene family is known for its role in cancer biology, particularly in testicular cancer and melanoma. The SPANXN1 gene, specifically, is expressed in normal testis and in various types of cancer.
Function[edit | edit source]
The SPANXN1 gene is part of the SPANX family of cancer/testis-associated genes, which are expressed in spermatozoa and in cancer cells. The exact function of the SPANXN1 gene is not fully understood, but it is believed to play a role in spermatogenesis and in the development of certain types of cancer.
Clinical significance[edit | edit source]
The SPANXN1 gene has been implicated in various types of cancer, including testicular cancer and melanoma. It is thought to be a potential target for cancer immunotherapy, as it is expressed in cancer cells but not in normal tissues, with the exception of the testis.
Research[edit | edit source]
Research into the SPANXN1 gene is ongoing, with studies focusing on its role in cancer development and its potential as a target for cancer immunotherapy. Further research is needed to fully understand the function of the SPANXN1 gene and its role in cancer biology.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
