Saflufenacil
Saflufenacil is a herbicide that is used to control a wide range of weed species. It is a member of the pyrimidinedione class of herbicides and is marketed under the trade name Sharpen by BASF.
Chemistry[edit | edit source]
Saflufenacil is a synthetic compound that is classified as a pyrimidinedione. It is a white, crystalline solid with a molecular formula of C14H9ClF3NO4S. The compound is highly soluble in water and has a low vapor pressure, making it suitable for use in a variety of agricultural applications.
Mode of Action[edit | edit source]
Saflufenacil works by inhibiting the enzyme protoporphyrinogen oxidase (PPO), which is essential for the synthesis of chlorophyll. This inhibition leads to the accumulation of protoporphyrin IX, which causes cell membrane damage and ultimately leads to plant death. The herbicide is effective against a wide range of weed species, including both broadleaf and grass weeds.
Use[edit | edit source]
Saflufenacil is used in a variety of agricultural settings, including crop fields, orchards, and vineyards. It can be applied pre-emergence or post-emergence, depending on the specific weed species and growth stage. The herbicide is often used in combination with other herbicides to provide broad-spectrum weed control.
Safety[edit | edit source]
Saflufenacil has a low acute toxicity to humans and is not considered to be a carcinogen. However, it can cause eye irritation and may be harmful if swallowed or inhaled. Appropriate personal protective equipment should be used when handling or applying the herbicide.
Environmental Impact[edit | edit source]
Saflufenacil is considered to be moderately persistent in the environment, with a half-life in soil of approximately 30 days. It has a low potential for bioaccumulation and is not expected to pose a significant risk to wildlife or aquatic organisms.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD