Sapanisertib

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<languages /><translate> An orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity and is an experimental drug.

Sapanisertib
Sapanisertib

Mechanism of action[edit | edit source]

Sapanisertib binds to and inhibits both TORC1 and TORC2 complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. TORC1 and 2 are upregulated in some tumors and play an important role in the PI3K/Akt/mTOR signaling pathway, which is frequently dysregulated in human cancers.

Clinical trials[edit | edit source]

Check for  ACTIVE CLINICAL TRIALS </translate>

Sapanisertib Resources
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