Schiller test

Schiller's Test is a medical procedure used primarily in the field of gynecology to detect early signs of cervical cancer. The test is named after Walter Schiller, an Austrian gynecologist who developed the technique in the early 20th century.

Procedure

The Schiller's Test involves the application of an iodine solution, known as Lugol's iodine, to the cervix. Healthy cervical tissue will absorb the iodine and turn brown, while potentially cancerous or precancerous areas, which contain less glycogen, will not absorb the iodine and will appear yellow or white. This contrast allows for the easy identification of abnormal areas that may require further testing or treatment.

Uses

While the Schiller's Test is not a definitive diagnostic tool for cervical cancer, it is often used as a preliminary screening method. It can also be used to delineate the borders of a lesion before a biopsy is performed. In addition, the Schiller's Test can be used to assess the extent of cervical intraepithelial neoplasia (CIN), a potential precursor to cervical cancer.

Limitations

The Schiller's Test has several limitations. It can produce false positives, as not all areas that fail to stain with iodine are cancerous or precancerous. Inflammation, for example, can also cause a negative iodine test. Furthermore, the test can only detect surface abnormalities and cannot identify cancerous cells that are located deeper within the cervical tissue.

See also

• Pap smear
• Colposcopy
• Cervical cancer

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