Side effects of cyproterone acetate

Cyproterone Acetate is a synthetic derivative of 17-hydroxyprogesterone, and is an antiandrogen, progestogen, and antigonadotropin. It is used in the treatment of conditions like prostate cancer, precocious puberty, and hypersexuality. However, like all medications, cyproterone acetate has potential side effects.

Side Effects

The side effects of cyproterone acetate can be categorized into common, uncommon, and rare side effects.

Common Side Effects

Common side effects include gynecomastia, weight gain, and depression. Gynecomastia, or enlargement of the male breasts, is a result of the antiandrogenic effects of the drug. Weight gain is often due to the drug's progestogenic effects, which can increase appetite. Depression is a potential neurological side effect.

Uncommon Side Effects

Uncommon side effects include liver damage, blood clots, and osteoporosis. Liver damage can occur due to the drug's potential hepatotoxicity. Blood clots are a risk due to the prothrombotic effects of the drug. Osteoporosis can occur due to the drug's antigonadotropic effects, which can decrease bone density.

Rare Side Effects

Rare side effects include meningioma, pulmonary embolism, and hepatic failure. Meningioma is a type of brain tumor that has been associated with long-term use of high-dose cyproterone acetate. Pulmonary embolism and hepatic failure are severe side effects that can be life-threatening.

See Also

• Antiandrogen
• Progestogen
• Antigonadotropin

References

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