Sodium cacodylate

Sodium cacodylate is a chemical compound with the formula Na(CH3)2AsO2. It is a white, crystalline solid that is commonly used in electron microscopy as a buffer solution. Sodium cacodylate is also known as dimethylarsinic acid sodium salt, cacodylic acid sodium salt, and sodium dimethylarsinate.

History

Sodium cacodylate was first synthesized in the 19th century. The term "cacodylate" comes from the Greek word "kakodes," which means "bad smelling," a reference to the compound's strong, unpleasant odor.

Chemical Properties

Sodium cacodylate is a sodium salt of dimethylarsinic acid. It is a white, crystalline solid that is soluble in water. The compound is stable under normal conditions, but it can decompose when heated, releasing toxic arsenic fumes.

Uses

Sodium cacodylate is most commonly used as a buffer in electron microscopy. It helps to maintain the pH of the sample, preventing unwanted reactions that could distort the image. The compound is also used in some types of DNA sequencing and in the synthesis of other chemical compounds.

Safety

Exposure to sodium cacodylate can be harmful. The compound is toxic if ingested, inhaled, or comes into contact with the skin. It can cause symptoms such as nausea, vomiting, diarrhea, and skin irritation. Long-term exposure can lead to more serious health effects, including damage to the liver and kidneys.

See Also

• Buffer solution
• Electron microscopy
• DNA sequencing