Solasodine

From WikiMD's Wellness Encyclopedia

Solasodine is a alkaloid compound that is found in plants of the Solanaceae family. It is a precursor to a variety of important pharmaceuticals, including steroids and glycoalkaloids.

Chemical Structure[edit | edit source]

Solasodine is a steroidal alkaloid, meaning it has a structure based on a steroid backbone with an additional nitrogen-containing group. Its chemical formula is C27H43NO2. The steroid backbone of solasodine is similar to that of cholesterol, but it has an additional nitrogen-containing group, which gives it its alkaloid properties.

Sources[edit | edit source]

Solasodine is found in plants of the Solanaceae family, which includes species such as Solanum nigrum (black nightshade), Solanum dulcamara (bittersweet), and Solanum melongena (eggplant). It is most commonly extracted from the berries of the Solanum nigrum plant.

Uses[edit | edit source]

Solasodine is used as a precursor in the synthesis of a variety of pharmaceuticals. It is particularly important in the production of steroids, as it can be converted into pregnenolone, which is a key intermediate in the biosynthesis of many steroids. Solasodine is also used in the production of glycoalkaloids, which have a range of biological activities and potential therapeutic uses.

Safety[edit | edit source]

While solasodine itself is not particularly toxic, many of the plants that contain it also contain other, more toxic alkaloids. Therefore, caution should be exercised when handling these plants or consuming products derived from them.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD