Solute carrier organic anion transporter family member 1A2
Solute carrier organic anion transporter family member 1A2 (SLCO1A2) is a protein that in humans is encoded by the SLCO1A2 gene. This protein is part of the solute carrier family and functions as an organic anion transporter.
Function[edit | edit source]
SLCO1A2 is involved in the transport of a wide variety of endogenous and exogenous organic anions. It plays a crucial role in the pharmacokinetics of many drugs by mediating their uptake into cells. This transporter is expressed in various tissues, including the liver, kidney, and brain, where it contributes to the absorption, distribution, and elimination of drugs and other compounds.
Clinical significance[edit | edit source]
Mutations or variations in the SLCO1A2 gene can affect the function of the transporter, potentially leading to altered drug response or drug toxicity. Understanding the role of SLCO1A2 in drug transport can help in the development of personalized medicine approaches, optimizing drug therapy based on individual genetic makeup.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
