Drug toxicity
Drug toxicity refers to the level of damage that a compound can cause to an organism. The toxicity of a drug is determined by the dose, the duration of exposure, the route of administration, and the individual's susceptibility.
Definition[edit | edit source]
Drug toxicity is the degree to which a substance (a toxin or poison) can harm humans or animals. Acute toxicity involves harmful effects in an organism through a single or short-term exposure. Chronic toxicity is the ability of a substance or mixture of substances to cause harmful effects over an extended period, usually upon repeated or continuous exposure, sometimes lasting for the entire life of the exposed organism.
Causes[edit | edit source]
Drug toxicity can be caused by many factors including the dose, the duration of exposure, the method of administration, the individual's age, sex, genetics, and overall health status. Some drugs are toxic in small amounts, while others require large amounts or prolonged use to cause toxicity.
Symptoms[edit | edit source]
Symptoms of drug toxicity can vary greatly depending on the type of drug, the dose, and the individual's sensitivity. They can range from mild symptoms such as nausea and vomiting, to severe symptoms such as seizures, heart problems, and even death.
Treatment[edit | edit source]
Treatment for drug toxicity depends on the specific drug involved. It may include discontinuing the drug, administering an antidote, supportive care such as IV fluids and monitoring vital signs, and in severe cases, hospitalization.
Prevention[edit | edit source]
Prevention of drug toxicity involves proper use of medications, including taking the correct dose, following the instructions for use, and regular monitoring for side effects. It also involves avoiding unnecessary use of medications, and regular check-ups with a healthcare provider.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD