Spindle cell hemangioma

Spindle Cell Hemangioma (SCH) is a rare type of vascular tumor that was first described in 1986 by Weiss and Enzinger. It was initially termed as "hemangioendothelioma," but was later renamed to Spindle Cell Hemangioma due to its benign nature and distinct clinical and pathological features.

Clinical Presentation

Spindle Cell Hemangiomas typically present as solitary or multiple nodules in the skin and subcutaneous tissues. They are most commonly found in the distal extremities, particularly the hands and feet. The lesions are often painful and may be associated with local trauma.

Pathology

Histologically, Spindle Cell Hemangiomas are characterized by cavernous blood vessels and spindle cell proliferations. The vascular spaces are often filled with blood and are lined by a single layer of endothelial cells. The spindle cells are thought to be modified endothelial cells and have a characteristic immunohistochemical profile.

Diagnosis

The diagnosis of Spindle Cell Hemangioma is primarily based on histopathological examination. Imaging studies such as MRI and ultrasound may be used to determine the extent of the lesion and to guide biopsy.

Treatment

The treatment of choice for Spindle Cell Hemangioma is surgical excision. In cases where surgery is not feasible, other treatment options may include radiotherapy and chemotherapy.

Prognosis

The prognosis of Spindle Cell Hemangioma is generally good, with a low rate of recurrence following surgical excision. However, the presence of multiple lesions may be associated with an underlying systemic condition such as Maffucci syndrome or Klippel-Trenaunay syndrome.

See Also

• Vascular tumor
• Hemangioma
• Maffucci syndrome
• Klippel-Trenaunay syndrome

References

Spindle cell hemangioma Resources
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