Spirapril hydrochloride

Spirapril hydrochloride - the hydrochloride salt form of spirapril, a prodrug and non sulfhydryl angiotensin converting enzyme (ace) inhibitor with antihypertensive activity. Spirapril is converted in the body to its active metabolite spiraprilat. Spiraprilat competitively binds to and inhibits ace, thereby blocking the conversion of angiotensin I to angiotensin ii. This prevents the potent vasoconstrictive actions of angiotensin ii and results in vasodilation. Spirapril also decreases angiotensin ii induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.

Resources[edit source]

Latest articles - Spirapril hydrochloride

This medical article is a stub. You can help WikiMD by expanding it.

‎ Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Spirapril hydrochloride for any updates.

‎

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.