Suvratoxumab

From WikiMD's Wellness Encyclopedia

Suvratoxumab is an experimental drug that is currently under development for the prevention of Staphylococcus aureus ventilator-associated pneumonia (VAP). It is a fully human monoclonal antibody that targets the alpha toxin produced by both methicillin-resistant and methicillin-susceptible S. aureus.

Mechanism of Action[edit | edit source]

Suvratoxumab works by neutralizing the alpha toxin produced by S. aureus. The alpha toxin is a major virulence factor that is responsible for the damage to host tissues and immune cells. By neutralizing this toxin, suvratoxumab can prevent the damage caused by S. aureus and potentially prevent the development of VAP.

Clinical Trials[edit | edit source]

Suvratoxumab has undergone Phase 2 clinical trials for the prevention of S. aureus VAP in mechanically ventilated patients. The results of these trials have shown that suvratoxumab is well-tolerated and has the potential to reduce the incidence of S. aureus VAP.

Potential Uses[edit | edit source]

If approved, suvratoxumab could be used in the prevention of S. aureus VAP in patients who are at high risk. This includes patients who are mechanically ventilated, as well as those with a history of S. aureus colonization or infection.

See Also[edit | edit source]

References[edit | edit source]


Suvratoxumab Resources
Wikipedia
WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD