Synaptogyrin 3
Synaptogyrin 3 is a protein that in humans is encoded by the SYNGR3 gene. It is a member of the synaptogyrin gene family and plays a crucial role in vesicle trafficking in neurons.
Function[edit | edit source]
Synaptogyrin 3 is a type of integral membrane protein found in neurons. It is primarily located in synaptic vesicles, small sacs in the neuron that store and release neurotransmitters. The exact function of synaptogyrin 3 is not fully understood, but it is believed to play a role in the trafficking of these vesicles, which is essential for neurotransmission.
Gene[edit | edit source]
The SYNGR3 gene is located on the short (p) arm of chromosome 22 at position 13.2. More precisely, the SYNGR3 gene is located from base pair 19,065,789 to base pair 19,075,789 on chromosome 22.
Clinical significance[edit | edit source]
Alterations in the SYNGR3 gene have been associated with various neurological disorders, including schizophrenia and bipolar disorder. However, more research is needed to fully understand the role of synaptogyrin 3 in these conditions.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
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Contributors: Prab R. Tumpati, MD
