TAAR5
TAAR5 (Trace Amine Associated Receptor 5) is a protein that is encoded in humans by the TAAR5 gene. It is a member of the Trace amine-associated receptor family, which is a group of G protein-coupled receptors that are predominantly expressed in the brain and are known to play a crucial role in neurological functions.
Function[edit | edit source]
TAAR5 is known to respond to the biogenic amine, 3-iodothyronamine, which is a naturally occurring amine that is derived from thyroid hormone metabolism. This interaction suggests that TAAR5 may play a role in the physiological functions that are regulated by the thyroid hormones.
Clinical significance[edit | edit source]
Alterations in the function of TAAR5 have been associated with a variety of neurological and psychiatric disorders, including schizophrenia, bipolar disorder, and depression. However, the exact role of TAAR5 in these conditions is not yet fully understood.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- TAAR5 at the US National Library of Medicine Medical Subject Headings (MeSH)
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Contributors: Prab R. Tumpati, MD
