TAS2R19

TAS2R19 is a gene that provides instructions for making a protein that is part of a family of taste receptors known as bitter taste receptors. These receptors are located on the surface of taste bud cells in the mouth and throat. They send signals to the brain in response to bitter compounds.

Function

The TAS2R19 protein is a member of the TAS2R taste receptor family. TAS2Rs are expressed in the taste receptor cells of the tongue and palate epithelia and mediate the perception of bitterness in the brain. They are involved in the gustatory perception which contributes to the sense of taste. The TAS2R19 gene is presumed to function in the perception of the bitterness of certain natural compounds.

Genetics

The TAS2R19 gene is located on the long (q) arm of chromosome 12 at position 13. More precisely, the TAS2R19 gene is located from base pair 11,080,711 to base pair 11,081,433 on chromosome 12.

Clinical significance

Variations in the TAS2R19 gene may influence taste perception, dietary behaviors, and potentially, metabolic disorders. However, more research is needed to fully understand the implications of these variations on health and disease.

See also

• Taste receptor
• TAS2R
• Chromosome 12