TAS2R7

TAS2R7 is a gene that encodes a protein known as a bitter taste receptor. This receptor is part of the TAS2R (Taste Receptor, Type 2) family of proteins, which are responsible for the perception of bitter taste in humans and other animals.

Function

The TAS2R7 protein is expressed in the taste bud cells of the tongue and palate epithelium. It is believed to play a crucial role in the detection of bitter-tasting compounds. The protein works by binding to specific chemicals in food and drink that are often associated with toxins, triggering a signal to the brain that the substance is potentially harmful.

Genetic Variation

Variations in the TAS2R7 gene can affect an individual's sensitivity to bitter tastes. Some people may have a version of the gene that makes them more sensitive to certain bitter compounds, while others may have a version that makes them less sensitive. This genetic variation can influence dietary choices and potentially impact health.

Clinical Significance

Research into TAS2R7 and other taste receptors may have significant implications for understanding and treating various health conditions. For example, manipulating the function of these receptors could potentially be used to change dietary preferences and manage obesity. Additionally, some studies suggest that taste receptors may also play a role in the respiratory system, indicating potential applications in treating conditions such as asthma and chronic obstructive pulmonary disease (COPD).

See Also

• TAS2R
• Taste bud
• Taste receptor
• Genetic variation