THU
THU or Tetrahydrocannabinol is one of at least 113 cannabinoids identified in cannabis. THC is the principal psychoactive constituent of cannabis. With chemical name (−)-trans-Δ⁹-tetrahydrocannabinol, the term THC also refers to cannabinoid isomers.
Chemistry[edit | edit source]
THC's chemical formula is C21H30O2, with a molecular mass of 314.464 g/mol. It is a glassy solid when cold, and becomes viscous and sticky if warmed. A pharmaceutical formulation of (−)-trans-Δ⁹-tetrahydrocannabinol, known by its INN dronabinol, is available by prescription in the U.S. and Canada under the brand name Marinol.
Pharmacology[edit | edit source]
THC, similar to other cannabinoids that contain a phenol group, possesses mild antioxidant activity sufficient to protect neurons against oxidative stress, such as that produced by glutamate-induced excitotoxicity.
Medical uses[edit | edit source]
THC is used in the treatment of nausea and vomiting; for which it has best evidence, and also for pain, inflammation, and spasticity.
Side effects[edit | edit source]
The most common effects of THC include relaxation, altered perception of time and space, increased appetite, and mood changes.
See also[edit | edit source]
References[edit | edit source]
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