TME (psychedelics)

Tryptamine, Monoamine and Ergoline (TME) Psychedelics

TME Psychedelics are a class of psychoactive substances that induce alterations in perception, mood, and cognitive processes. They are derived from three main classes of compounds: Tryptamines, Monoamines, and Ergolines.

Tryptamines

Tryptamines are a group of compounds structurally derived from tryptamine, a monoamine alkaloid. They are known for their psychoactive properties, which can induce states of altered perception, mood, and thought. Some well-known tryptamines include Dimethyltryptamine (DMT), Psilocybin, and LSD.

Monoamines

Monoamines are a class of neurotransmitters derived from aromatic amino acids like phenylalanine, tyrosine, and tryptophan. They play a crucial role in regulating numerous physiological functions, including mood, attention, and focus. Some monoamines, such as Dopamine, Serotonin, and Norepinephrine, are also involved in the action of many psychedelic substances.

Ergolines

Ergolines are a class of compounds derived from ergoline, a tetracyclic alkaloid. They are known for their psychoactive properties and are commonly found in substances like LSD and Ergotamine. Ergolines can induce profound changes in consciousness, often characterized by intense visual hallucinations and altered thought processes.

Pharmacology

The pharmacological action of TME psychedelics primarily involves the agonism or partial agonism of serotonin receptors in the brain, particularly the 5-HT2A receptor. This receptor subtype is thought to play a key role in the cognitive and perceptual effects of psychedelics.

Safety and Risks

While TME psychedelics are generally considered non-addictive, they carry risks, including psychological distress, dangerous behavior, and potential legal consequences. It is important to use these substances responsibly and under the guidance of a healthcare professional.

See Also

• Psychedelic Therapy
• Hallucinogen
• Psychedelic Experience
• Serotonergic Psychedelic