Death receptor 5

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death receptor 5 (… reh-SEP-ter 5) A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells. An increase in the amount or activity of death receptor 5 on cancer cells may kill more cells. Also called DR5, TRAIL receptor 2, TRAIL-R2, and tumor necrosis factor receptor superfamily member 10B.

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Contributors: Prab R. Tumpati, MD