TOET (psychedelic)

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TOET (psychedelic)

TOET, also known as 2,5-dimethoxy-4-ethylthiophenethylamine, is a psychedelic drug and a member of the 2C family of psychedelics. It was first synthesized by Alexander Shulgin and documented in his book PiHKAL.

Chemistry[edit | edit source]

TOET is a phenethylamine, which is a broad class of chemicals that also includes other psychedelic substances like mescaline and 2C-B. The full chemical name of TOET is 2,5-dimethoxy-4-ethylthiophenethylamine. The structure of TOET includes a phenethylamine core, which is a phenyl ring bound to an amino (NH2) group through an ethyl chain. TOET has two methoxy functional groups CH3O- attached to carbons R2 and R5 as well as an ethylthio group attached to carbon R4 of the phenyl ring.

Pharmacology[edit | edit source]

Like other 2C drugs, TOET is believed to work by binding to and activating the serotonin 2A receptor, which significantly affects the brain's neurotransmission. However, the exact mechanisms of its action are not fully understood, and more research is needed in this area.

Effects[edit | edit source]

The effects of TOET are similar to other 2C drugs and can include hallucinations, enhanced colors, and increased awareness of sounds. However, the effects can vary greatly depending on the individual, the dose taken, and the method of ingestion. It is worth noting that the use of TOET, like other psychedelic drugs, can also lead to negative effects such as anxiety, paranoia, and dangerous changes in behavior or perception.

Legality[edit | edit source]

The legality of TOET varies from country to country. In some countries, it is classified as a controlled substance, while in others it is completely legal. It is always important to understand the legal status of TOET in your jurisdiction before possession or use.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD