TRADD
TRADD is a protein that in humans is encoded by the TRADD gene. TRADD stands for TNFRSF1A-associated via death domain. It is a death domain-containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation.
Function[edit | edit source]
TRADD is a cell signaling adaptor protein that is involved in the TNF receptor pathway. It is a crucial component of the TNF-alpha signaling pathway and interacts with tumor necrosis factor receptor (TNFRSF1A/TNFR1) to mediate programmed cell death and NF-kappaB activation.
Clinical significance[edit | edit source]
Mutations in the TRADD gene have been associated with various diseases. For instance, it has been implicated in the pathogenesis of cancer, autoimmune diseases, and inflammatory diseases.
Interactions[edit | edit source]
TRADD has been shown to interact with:
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- TRADD at the US National Library of Medicine Medical Subject Headings (MeSH)
| TRADD Resources | ||
|---|---|---|
|
| |
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Contributors: Prab R. Tumpati, MD
