TSPAN12
TSPAN12 is a protein that in humans is encoded by the TSPAN12 gene. It is a member of the tetraspanin superfamily, which is known for its role in cell development, activation, growth and motility. TSPAN12 is involved in the regulation of cell development and can influence various processes such as proliferation, differentiation, and adhesion.
Function[edit | edit source]
TSPAN12 is a transmembrane protein that is involved in the regulation of cell development. It is known to interact with other proteins, such as ADAM10, to influence cell proliferation, differentiation, and adhesion. TSPAN12 is also involved in the regulation of angiogenesis, the process by which new blood vessels form from pre-existing vessels.
Clinical significance[edit | edit source]
Mutations in the TSPAN12 gene are associated with Familial exudative vitreoretinopathy (FEVR), a hereditary disorder that can cause progressive vision loss. This condition is characterized by the failure of peripheral retinal vascularization, which can lead to retinal detachment and blindness.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
| TSPAN12 Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
