Taurocholic acid

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(Redirected from Taurocholate)

style="background: #F8EABA; text-align: center;" colspan="2" Taurocholic acid
Taurocholic acid
Chemical name 2-{[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-
24-oxocholan-24-yl]amino}ethanesulfonic acid
Chemical formula C26H45NO7S
Molecular mass 515.7058 g/mol
CAS number [81-24-3]
Density x.xxx g/cm3
Melting point 125.0 °C
Boiling point xx.x °C
style="background: #F8EABA; text-align: center;" colspan="2" Disclaimer and references

Taurocholic acid is a prominent bile acid, instrumental in the process of fat emulsification. Recognized by several other names such as cholaic acid, cholyltaurine, and acidum cholatauricum, it primarily exists as a sodium salt in mammalian bile. Structurally, it is a conjugate formed by the combination of cholic acid and taurine. Both medically and commercially, taurocholic acid finds varied applications and is primarily derived from cattle bile.

Overview[edit | edit source]

As a yellowish crystalline substance that is deliquescent, taurocholic acid plays an indispensable role in the digestive system. Its primary function involves assisting in the emulsification of fats, a critical step in digestion that facilitates the absorption of dietary lipids.

Medical Significance[edit | edit source]

In the field of medicine, taurocholic acid is revered for its cholagogue and cholerectic properties. These attributes make it useful for:

  • Stimulating bile production in the liver.
  • Enhancing bile secretion into the small intestine, which aids in the digestion and absorption of dietary fats.

Hydrolysis and Taurine[edit | edit source]

Upon undergoing hydrolysis, taurocholic acid yields taurine, a nonessential amino acid that has several functions in the body. Taurine is pivotal for various physiological processes, including:

  • Regulating mineral balance in cells.
  • Antioxidant activities.
  • Modulating immune system health.
  • Contributing to the proper function of the central nervous system.

Commercial Production[edit | edit source]

On a commercial scale, taurocholic acid is predominantly extracted from cattle bile, which is readily available as a byproduct of the meat-processing industry. This ensures efficient utilization of animal byproducts while also catering to medical and commercial needs.

See Also[edit | edit source]

References[edit | edit source]

See also[edit | edit source]

Taurocholic acid Resources
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Contributors: Prab R. Tumpati, MD