Taurocholic acid
| style="background: #F8EABA; text-align: center;" colspan="2" | Taurocholic acid |
|---|---|
| Taurocholic acid | |
| Chemical name | 2-{[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy- 24-oxocholan-24-yl]amino}ethanesulfonic acid |
| Chemical formula | C26H45NO7S |
| Molecular mass | 515.7058 g/mol |
| CAS number | [81-24-3] |
| Density | x.xxx g/cm3 |
| Melting point | 125.0 °C |
| Boiling point | xx.x °C |
| style="background: #F8EABA; text-align: center;" colspan="2" | Disclaimer and references |
Taurocholic acid is a prominent bile acid, instrumental in the process of fat emulsification. Recognized by several other names such as cholaic acid, cholyltaurine, and acidum cholatauricum, it primarily exists as a sodium salt in mammalian bile. Structurally, it is a conjugate formed by the combination of cholic acid and taurine. Both medically and commercially, taurocholic acid finds varied applications and is primarily derived from cattle bile.
Overview[edit | edit source]
As a yellowish crystalline substance that is deliquescent, taurocholic acid plays an indispensable role in the digestive system. Its primary function involves assisting in the emulsification of fats, a critical step in digestion that facilitates the absorption of dietary lipids.
Medical Significance[edit | edit source]
In the field of medicine, taurocholic acid is revered for its cholagogue and cholerectic properties. These attributes make it useful for:
- Stimulating bile production in the liver.
- Enhancing bile secretion into the small intestine, which aids in the digestion and absorption of dietary fats.
Hydrolysis and Taurine[edit | edit source]
Upon undergoing hydrolysis, taurocholic acid yields taurine, a nonessential amino acid that has several functions in the body. Taurine is pivotal for various physiological processes, including:
- Regulating mineral balance in cells.
- Antioxidant activities.
- Modulating immune system health.
- Contributing to the proper function of the central nervous system.
Commercial Production[edit | edit source]
On a commercial scale, taurocholic acid is predominantly extracted from cattle bile, which is readily available as a byproduct of the meat-processing industry. This ensures efficient utilization of animal byproducts while also catering to medical and commercial needs.
See Also[edit | edit source]
References[edit | edit source]
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
