Telmisartan/hydrochlorothiazide

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Telmisartan/hydrochlorothiazide is a medication combination used in the treatment of hypertension. It combines two active ingredients, telmisartan and hydrochlorothiazide, which work together to lower blood pressure.

Etymology[edit | edit source]

The name "telmisartan" is derived from the components of the drug: "telmi" is short for telmisartan, and "sartan" refers to the class of drugs known as angiotensin II receptor antagonists. The name "hydrochlorothiazide" is derived from its chemical structure, which includes a hydrochloride group and a thiazide group.

Pharmacology[edit | edit source]

Telmisartan is an angiotensin II receptor antagonist that works by blocking the action of angiotensin II, a chemical in the body that causes blood vessels to constrict. This helps to relax and widen blood vessels, reducing blood pressure.

Hydrochlorothiazide is a diuretic that helps the kidneys to remove excess fluid and salt from the body, which can help to lower blood pressure.

Indications[edit | edit source]

Telmisartan/hydrochlorothiazide is indicated for the treatment of hypertension in adults who are not adequately controlled on monotherapy with either telmisartan or hydrochlorothiazide, or for those patients who have initially responded to telmisartan and are expected to benefit from combined therapy.

Side Effects[edit | edit source]

Common side effects of telmisartan/hydrochlorothiazide include dizziness, fatigue, and headache. More serious side effects can include kidney problems, liver problems, and electrolyte imbalances.

Related Terms[edit | edit source]

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Contributors: Prab R. Tumpati, MD