Tetrachlorvinphos

Organophosphate insecticide and acaricide

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Tetrachlorvinphos is an organophosphate insecticide and acaricide used primarily in veterinary medicine and pest control. It is effective against a wide range of insects and is commonly used in livestock and pet products to control fleas, ticks, and other pests.

Chemical Properties

Tetrachlorvinphos is a phosphoric acid ester with the chemical formula C₁₀H₉Cl₄O₄P. It is a white to tan crystalline solid with a slight odor. The compound is relatively stable under normal conditions but can decompose when exposed to heat or alkaline conditions.

Mechanism of Action

As an organophosphate, tetrachlorvinphos functions by inhibiting acetylcholinesterase, an enzyme essential for the proper functioning of the nervous system in insects. This inhibition leads to the accumulation of acetylcholine at synapses, causing continuous nerve impulse transmission, paralysis, and eventually death of the insect.

Uses

Tetrachlorvinphos is used in various formulations, including dust, spray, and collar forms, to control ectoparasites on animals. It is commonly applied to cattle, swine, poultry, and companion animals such as dogs and cats.

Veterinary Applications

In veterinary settings, tetrachlorvinphos is used to manage ectoparasitic infestations in livestock, helping to improve animal health and productivity. It is also used in pet care products, such as flea collars and shampoos, to protect pets from fleas and ticks.

Agricultural and Domestic Uses

In agriculture, tetrachlorvinphos is applied to control pests in grain storage and processing facilities. It is also used in domestic settings to manage household pests like flies and cockroaches.

Safety and Environmental Impact

While effective, tetrachlorvinphos poses potential risks to human health and the environment. It is classified as a possible carcinogen by the International Agency for Research on Cancer (IARC). Proper handling and application are essential to minimize exposure and environmental contamination.

Human Health Concerns

Exposure to tetrachlorvinphos can occur through inhalation, ingestion, or dermal contact. Symptoms of acute exposure include headache, dizziness, nausea, and muscle weakness. Chronic exposure may lead to more severe health effects, including neurological damage.

Environmental Considerations

Tetrachlorvinphos can persist in the environment and may affect non-target organisms, including beneficial insects, birds, and aquatic life. It is important to follow regulatory guidelines and label instructions to reduce environmental impact.

Regulation

The use of tetrachlorvinphos is regulated by various national and international agencies to ensure safety for humans and the environment. In the United States, it is registered under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and subject to periodic review by the Environmental Protection Agency (EPA).

Related Pages

• Organophosphate
• Insecticide
• Acaricide
• Acetylcholinesterase
• Pesticide regulation