Thiacetarsamide

Thiacetarsamide is a drug used in the treatment of canine heartworm disease. It is an organic compound containing arsenic, and is administered by intravenous injection.

Chemistry

Thiacetarsamide, also known as Caparsolate, is an organoarsenic compound. Its chemical formula is C4H8As2S6, and it is a yellow, crystalline solid at room temperature. The compound is soluble in water and is typically administered in a solution.

Pharmacology

Thiacetarsamide works by inhibiting the growth of Dirofilaria immitis, the parasite that causes heartworm disease in dogs. It does this by interfering with the parasite's ability to metabolize glucose, which is essential for its survival.

Usage

Thiacetarsamide is administered by intravenous injection, usually in the back of the dog's leg. The drug is given in a series of injections over a period of several days. The exact dosage and schedule of injections will depend on the severity of the dog's heartworm infection.

Side Effects

Like all drugs, thiacetarsamide can have side effects. These can include vomiting, diarrhea, loss of appetite, and lethargy. In rare cases, dogs may have an allergic reaction to the drug, which can cause symptoms such as difficulty breathing, hives, and swelling of the face, lips, tongue, or throat.

Precautions

Before starting treatment with thiacetarsamide, it is important to have a thorough veterinary examination to determine the extent of the heartworm infection and the overall health of the dog. Dogs with severe heartworm disease or other health problems may not be good candidates for treatment with thiacetarsamide.

See Also

• Heartworm
• Dirofilaria immitis
• Canine heartworm disease
• Intravenous injection