Thiamylal sodium

Thiamylal Sodium is a barbiturate derivative that is used as an anesthetic. It is a short-acting barbiturate that is typically used for induction of anesthesia in surgical procedures.

History

Thiamylal Sodium was first synthesized in the 1950s as part of a series of barbiturates developed for medical use. It was initially used as a sedative and hypnotic, but its use has since expanded to include anesthesia.

Pharmacology

Thiamylal Sodium works by increasing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits the activity of the nervous system. This results in sedation, hypnosis, and ultimately, anesthesia.

Medical Uses

Thiamylal Sodium is primarily used as an induction agent for general anesthesia. It is also used for sedation in intensive care units and for the treatment of convulsive status epilepticus.

Side Effects

Like other barbiturates, Thiamylal Sodium can cause a range of side effects, including drowsiness, dizziness, and respiratory depression. In rare cases, it can cause severe allergic reactions.

See Also

• Barbiturate
• Anesthesia
• Gamma-aminobutyric acid

References

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