Thiothixene

Thiothixene is a type of antipsychotic medication that is used primarily in the treatment of schizophrenia. It belongs to the class of drugs known as typical antipsychotics, which work by altering the effects of chemicals in the brain.

Pharmacology

Thiothixene acts by blocking postsynaptic dopamine receptors in the brain, including D1, D2, D3 and D4 receptors. This reduces dopamine transmission, which is thought to alleviate symptoms of schizophrenia.

Medical uses

Thiothixene is used in the treatment of schizophrenia and other types of psychosis. It can help to reduce symptoms such as hallucinations, delusions, and disorganized thinking. It may also be used to treat severe behavioral problems in children when other treatments have not been effective.

Side effects

Common side effects of thiothixene include drowsiness, dizziness, and dry mouth. More serious side effects can include tardive dyskinesia, a condition characterized by involuntary movements, and neuroleptic malignant syndrome, a potentially life-threatening reaction to antipsychotic drugs.

History

Thiothixene was first synthesized in the 1950s and was approved for medical use in the United States in 1967. It is available as a generic medication.

See also

• List of antipsychotics
• Schizophrenia
• Psychosis

Thiothixene Resources
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