Tomatinase

From WikiMD.com Medical Encyclopedia

Tomatinase is an enzyme that is involved in the breakdown of tomatine, a toxic glycoalkaloid found in the leaves and stems of tomato plants. This enzyme is produced by certain types of fungi and bacteria, and plays a crucial role in their ability to infect tomato plants.

Function[edit | edit source]

Tomatinase functions by cleaving the sugar moiety from tomatine, rendering it non-toxic. This allows the organism producing the tomatase to survive in the presence of tomatine, and to use the sugar as a source of energy. The enzyme is typically produced when the organism comes into contact with tomatine, suggesting that it is a response to the presence of this toxic compound.

Structure[edit | edit source]

The structure of tomatinase is not fully understood, but it is believed to be a protein composed of several amino acid sequences. These sequences are arranged in a specific order, which determines the shape and function of the enzyme. The active site of the enzyme, where the breakdown of tomatine occurs, is thought to contain several key amino acids that interact with the tomatine molecule.

Role in Plant Pathology[edit | edit source]

Tomatinase is a key factor in the ability of certain fungi and bacteria to infect tomato plants. These organisms are able to survive in the presence of tomatine, and can even use it as a source of energy, thanks to the action of tomatinase. This makes tomatinase a potential target for the development of new pesticides and fungicides.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD