Trabeculae of spleen

Trabeculae of Spleen

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Anatomy of the spleen, showing the trabeculae

The trabeculae of the spleen are small, fibrous bands that extend from the spleen's capsule into the organ's interior. These structures play a crucial role in the spleen's function and structure, providing a framework that supports the organ's cellular components.

Structure

The trabeculae of the spleen are composed of collagen fibers and smooth muscle cells. They originate from the tunica albuginea, a dense layer of connective tissue that surrounds the spleen. From there, the trabeculae extend into the organ, dividing it into numerous smaller compartments or lobules.

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Microscopic view of the spleen showing the trabeculae

Function

The trabeculae of the spleen serve several important functions. They provide structural support to the spleen, helping to maintain its shape and integrity. They also serve as conduits for blood vessels, nerves, and lymphatic vessels, allowing these structures to penetrate into the spleen's interior.

In addition, the trabeculae play a role in the spleen's immune function. They help to compartmentalize the organ, creating distinct areas where different types of immune cells can congregate and interact.

Clinical Significance

Abnormalities in the trabeculae of the spleen can have significant clinical implications. For example, in conditions such as splenomegaly, the trabeculae can become stretched and thinned, potentially leading to rupture of the spleen. Conversely, in conditions such as splenic atrophy, the trabeculae can become thickened and fibrotic, impairing the spleen's function.

See Also

• Spleen
• Lymphatic system
• Immune system