Trelagliptin
Trelagliptin is a medication used for the treatment of Type 2 diabetes. It is classified as a Dipeptidyl peptidase-4 inhibitor (DPP-4 inhibitor), a class of drugs that work by blocking the action of DPP-4, an enzyme that destroys the hormone Incretin. This results in increased levels of Incretin hormones, which help to control blood sugar by increasing insulin production and decreasing glucagon production.
Etymology[edit | edit source]
The name "Trelagliptin" is derived from the chemical structure of the drug, which includes a triazole ring (tre), a leucine moiety (lag), and a piperidine ring (liptin).
Pharmacology[edit | edit source]
Trelagliptin works by inhibiting the enzyme Dipeptidyl peptidase-4 (DPP-4). This enzyme is involved in the breakdown of the incretin hormones GLP-1 and GIP. By inhibiting DPP-4, trelagliptin increases the levels of these hormones, leading to increased insulin production and decreased glucagon production. This helps to control blood sugar levels in people with type 2 diabetes.
Clinical Use[edit | edit source]
Trelagliptin is used for the treatment of Type 2 diabetes. It is typically used in combination with diet and exercise to improve blood sugar control in adults with type 2 diabetes. Trelagliptin is not used for the treatment of type 1 diabetes or diabetic ketoacidosis.
Side Effects[edit | edit source]
Common side effects of trelagliptin include headache, upper respiratory tract infection, and nasopharyngitis. Serious side effects may include pancreatitis and hypersensitivity reactions.
Related Terms[edit | edit source]
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