Trelagliptin

Trelagliptin is a medication used for the treatment of Type 2 diabetes. It is classified as a Dipeptidyl peptidase-4 inhibitor (DPP-4 inhibitor), a class of drugs that work by blocking the action of DPP-4, an enzyme that destroys the hormone Incretin. This results in increased levels of Incretin hormones, which help to control blood sugar by increasing insulin production and decreasing glucagon production.

Etymology[edit | edit source]

The name "Trelagliptin" is derived from the chemical structure of the drug, which includes a triazole ring (tre), a leucine moiety (lag), and a piperidine ring (liptin).

Pharmacology[edit | edit source]

Trelagliptin works by inhibiting the enzyme Dipeptidyl peptidase-4 (DPP-4). This enzyme is involved in the breakdown of the incretin hormones GLP-1 and GIP. By inhibiting DPP-4, trelagliptin increases the levels of these hormones, leading to increased insulin production and decreased glucagon production. This helps to control blood sugar levels in people with type 2 diabetes.

Clinical Use[edit | edit source]

Trelagliptin is used for the treatment of Type 2 diabetes. It is typically used in combination with diet and exercise to improve blood sugar control in adults with type 2 diabetes. Trelagliptin is not used for the treatment of type 1 diabetes or diabetic ketoacidosis.

Side Effects[edit | edit source]

Common side effects of trelagliptin include headache, upper respiratory tract infection, and nasopharyngitis. Serious side effects may include pancreatitis and hypersensitivity reactions.

Related Terms[edit | edit source]

Trelagliptin Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.