Trematode mitochondrial code

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Trematode Mitochondrial Code is a variant of the standard genetic code used by trematodes, a class of parasitic flatworms, in their mitochondria. This code is unique to trematodes and differs from the standard genetic code in several key ways.

Overview[edit | edit source]

The genetic code is a set of rules used by living cells to translate information encoded in genetic material (DNA or mRNA sequences) into proteins. In the standard genetic code, each three-nucleotide sequence (codon) corresponds to a specific amino acid or a stop signal. The trematode mitochondrial code, however, has several unique features that distinguish it from the standard code.

Differences from the Standard Code[edit | edit source]

The trematode mitochondrial code differs from the standard code in the following ways:

  • The codon UGA, which codes for a stop signal in the standard code, codes for the amino acid tryptophan in the trematode mitochondrial code.
  • The codon AUA, which codes for the amino acid isoleucine in the standard code, codes for the amino acid methionine in the trematode mitochondrial code.
  • The codon AGA and AGG, which code for the amino acid arginine in the standard code, are stop codons in the trematode mitochondrial code.

Implications[edit | edit source]

These differences in the genetic code have significant implications for the biology of trematodes. For example, they may affect the efficiency of protein synthesis, the structure and function of proteins, and the evolution of the mitochondrial genome.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD