Triflunordazepam

Triflunordazepam is a benzodiazepine derivative drug with anxiolytic, anticonvulsant, hypnotic, amnesic, sedative, and skeletal muscle relaxant properties. It is an active metabolite of the parent drug flurazepam, and is believed to be partially responsible for its effects.

Pharmacology

Triflunordazepam, like other benzodiazepines, works by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain, leading to sedative and anxiolytic effects. It is metabolized in the liver by the cytochrome P450 enzyme system and its metabolites are excreted in the urine.

Medical uses

Triflunordazepam is used primarily as a treatment for anxiety disorders, insomnia, and seizures. It may also be used as a premedication for inducing sedation, anxiolysis, or amnesia before certain medical procedures.

Side effects

Common side effects of triflunordazepam include drowsiness, dizziness, and loss of coordination. Less common side effects can include confusion, depression, and memory impairment. Long-term use of triflunordazepam can lead to tolerance, dependence, and withdrawal syndrome upon discontinuation.

See also

• Benzodiazepine
• Flurazepam
• GABA