Triflunordazepam
A benzodiazepine derivative
| Triflunordazepam | |
|---|---|
| |
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | |
| PubChem | |
| DrugBank | |
| ChemSpider | |
| KEGG | |
Triflunordazepam is a benzodiazepine derivative that is used for its anxiolytic, sedative, and muscle relaxant properties. It is a psychoactive drug that acts on the central nervous system by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA_A receptor.
Pharmacology[edit | edit source]
Triflunordazepam, like other benzodiazepines, works by binding to the benzodiazepine site on the GABA_A receptor. This binding increases the frequency of chloride ion channel opening events, leading to an increased inhibitory effect of GABA in the central nervous system. This results in the drug's calming effects, making it useful in the treatment of anxiety disorders, insomnia, and muscle spasms.
Clinical Use[edit | edit source]
Triflunordazepam is primarily prescribed for the management of severe anxiety and insomnia. It may also be used as a premedication for anesthesia or for the treatment of seizures in certain cases. Due to its potential for dependence and tolerance, it is generally recommended for short-term use.
Side Effects[edit | edit source]
Common side effects of triflunordazepam include drowsiness, dizziness, and fatigue. More serious side effects can include respiratory depression, hypotension, and paradoxical reactions such as increased anxiety or aggression. Long-term use can lead to physical dependence and withdrawal symptoms upon discontinuation.
Legal Status[edit | edit source]
The legal status of triflunordazepam varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and dependence. It is important for prescribers to adhere to local regulations when prescribing this medication.
Related pages[edit | edit source]
Triflunordazepam
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
