Trophoblastic

Trophoblastic Disease

Trophoblastic disease is a group of rare tumors that involve abnormal growth of cells inside a woman's uterus. Trophoblastic disease almost always occurs as a result of pregnancy. The two main types of trophoblastic disease are Hydatidiform Mole and Choriocarcinoma.

Types of Trophoblastic Disease

Hydatidiform Mole

A Hydatidiform Mole is a type of gestational trophoblastic disease that occurs when the fertilization of an egg by a sperm results in an abnormal pregnancy. There are two types of hydatidiform moles: complete and partial.

Complete Hydatidiform Mole

A complete hydatidiform mole occurs when an empty egg is fertilized by one or two sperm, and all the genetic material is from the father.

Partial Hydatidiform Mole

A partial hydatidiform mole occurs when a normal egg is fertilized by two sperm or by one sperm that duplicates itself, resulting in an embryo with too many chromosomes.

Choriocarcinoma

Choriocarcinoma is a rare and aggressive form of cancer that occurs in a woman's uterus (womb). The disease is a type of gestational trophoblastic disease (GTD).

Symptoms

The symptoms of trophoblastic disease can vary depending on the type. Common symptoms include vaginal bleeding, severe nausea and vomiting, and early preeclampsia.

Diagnosis

Trophoblastic disease can be diagnosed through a series of tests, including a pregnancy test, ultrasound, and blood tests to measure the level of human chorionic gonadotropin (hCG).

Treatment

Treatment for trophoblastic disease depends on the type of disease, the patient's age, and the patient's overall health. Treatment options include surgery, chemotherapy, and radiation therapy.

See Also

• Gestational Trophoblastic Disease
• Molar Pregnancy
• Choriocarcinoma

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