Troxipide
Troxipide is a gastrointestinal medication primarily used in the treatment of gastric ulcers and duodenal ulcers. It is a pyridine derivative and functions as a gastric mucosal protective agent. Troxipide is not available in all countries and is most commonly used in Asia and Europe.
Mechanism of Action[edit | edit source]
Troxipide works by increasing the production of prostaglandins, which are chemicals that help protect the stomach lining. Prostaglandins increase the secretion of mucus and bicarbonate, substances that are protective against stomach acid. Additionally, troxipide inhibits the secretion of gastric acid, further protecting the stomach lining.
Indications[edit | edit source]
Troxipide is indicated for the treatment of gastric and duodenal ulcers. It may also be used for the treatment of gastritis, esophagitis, and gastroesophageal reflux disease (GERD).
Side Effects[edit | edit source]
Common side effects of troxipide include nausea, vomiting, abdominal pain, and diarrhea. Less common side effects may include dizziness, headache, and rash.
Contraindications[edit | edit source]
Troxipide is contraindicated in patients with known hypersensitivity to the drug. It should be used with caution in patients with renal impairment or liver disease.
Interactions[edit | edit source]
Troxipide may interact with other medications, including antacids, proton pump inhibitors, and H2 receptor antagonists. Patients should inform their healthcare provider of all medications they are currently taking.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
