Codeine/paracetamol

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Codeine/Paracetamol is a compound analgesic, a combination of a mild opioid, codeine, and a non-opioid pain reliever, paracetamol (also known as acetaminophen). This combination is used to treat moderate to severe pain.

Etymology[edit | edit source]

The term "codeine" is derived from the Greek word "kodeia," which means "poppy head." Paracetamol's name is derived from its chemical name, para-acetylaminophenol.

Pharmacology[edit | edit source]

Codeine is a prodrug, which means it is metabolized in the body to produce its active form, morphine. Paracetamol, on the other hand, is believed to work by reducing the production of prostaglandins in the brain and spinal cord.

Uses[edit | edit source]

Codeine/paracetamol is used to treat moderate to severe pain, such as pain following surgery or injury. It is also used for the relief of chronic conditions such as rheumatoid arthritis.

Side Effects[edit | edit source]

Common side effects of codeine/paracetamol include dizziness, lightheadedness, nausea, vomiting, shortness of breath, and sedation. More serious side effects may include respiratory depression and hepatotoxicity.

Related Terms[edit | edit source]

  • Analgesic: A class of drugs used to relieve pain.
  • Opioid: A type of narcotic drug that is used to treat severe pain.
  • Prodrug: A medication that is metabolized in the body to produce its active form.
  • Hepatotoxicity: Damage to the liver caused by a drug or other chemical substance.

See Also[edit | edit source]

Codeine/paracetamol Resources
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Contributors: Prab R. Tumpati, MD