Tyropanoate sodium

Tyropanoate Sodium is a radiocontrast agent used in cholecystography, a diagnostic imaging procedure for the gallbladder. It is a type of iodinated contrast agent, which are compounds containing iodine atoms used to enhance the visibility of internal structures in X-ray based imaging techniques.

Chemical Structure

Tyropanoate Sodium is a sodium salt of tyropanoic acid. Its chemical formula is C15H9I4NO3Na. The compound contains four iodine atoms, which are responsible for its radio-opaque properties. The iodine atoms absorb X-rays and appear white on the resulting images, providing contrast against the surrounding tissues.

Mechanism of Action

Tyropanoate Sodium works by inhibiting the enzyme iodotyrosine deiodinase, which is involved in the recycling of iodine in the body. This inhibition leads to a decrease in the production of thyroid hormones, which in turn reduces the amount of iodine available for uptake by the gallbladder. As a result, the gallbladder fills with the contrast agent, allowing it to be clearly visualized on an X-ray image.

Uses

Tyropanoate Sodium is primarily used in cholecystography, a procedure used to visualize the gallbladder and diagnose conditions such as gallstones and cholecystitis. It may also be used in other imaging procedures where it is necessary to visualize the biliary tract.

Side Effects

Like all contrast agents, Tyropanoate Sodium can cause side effects. These may include allergic reactions, nausea, vomiting, and diarrhea. In rare cases, serious reactions such as anaphylaxis can occur.

See Also

• Iodinated contrast
• Cholecystography
• Gallstones
• Cholecystitis