Ulobetasol propionate
Overview of Ulobetasol propionate
| Ulobetasol propionate | |
|---|---|
| |
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | |
| PubChem | |
| DrugBank | |
| ChemSpider | |
| KEGG | |
Ulobetasol propionate is a corticosteroid used in the treatment of various skin conditions. It is known for its potent anti-inflammatory properties and is often prescribed for short-term management of dermatological disorders.
Pharmacology[edit | edit source]
Ulobetasol propionate is a topical corticosteroid that works by reducing inflammation and suppressing the immune response in the skin. It is classified as a super-high potency corticosteroid, making it effective for severe skin conditions that do not respond to less potent treatments.
Mechanism of Action[edit | edit source]
The mechanism of action of ulobetasol propionate involves the induction of lipocortin, which inhibits phospholipase A2. This action reduces the release of arachidonic acid, a precursor of prostaglandins and leukotrienes, which are mediators of inflammation.
Clinical Uses[edit | edit source]
Ulobetasol propionate is primarily used for the treatment of psoriasis, eczema, and other inflammatory skin conditions. It is typically applied as a cream or ointment and is intended for short-term use due to its potency.
Application[edit | edit source]
The medication is applied to the affected area of the skin, usually once or twice daily. It is important to follow the prescribed dosage and duration to minimize the risk of side effects.
Side Effects[edit | edit source]
Common side effects of ulobetasol propionate include skin irritation, dryness, and hypopigmentation. Prolonged use can lead to more serious side effects such as skin atrophy, telangiectasia, and adrenal suppression.
Precautions[edit | edit source]
Patients using ulobetasol propionate should be monitored for signs of HPA axis suppression, especially if used over large surface areas or for extended periods. It is not recommended for use in children or on the face, groin, or underarms unless directed by a healthcare provider.
Related pages[edit | edit source]
Ulobetasol propionate
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
