Undecylprodigiosin

Undecylprodigiosin is a secondary metabolite produced by several strains of bacteria, including Streptomyces coelicolor and Serratia marcescens. It is a member of the prodigiosin family of compounds, which are characterized by their red pigmentation and potential therapeutic applications.

Structure and Synthesis

Undecylprodigiosin is a linear tripyrrole molecule, with a chemical formula of C₂₅H₃₃N₃O. Its structure consists of three pyrrole rings linked by methine bridges, with an undecyl side chain attached to one of the rings. The molecule is synthesized by the bacteria through a complex pathway involving several enzymes, including Prodigiosin synthase.

Biological Activity

Undecylprodigiosin has been shown to have several biological activities, including antibiotic, antifungal, antiprotozoal, and anticancer properties. Its mechanism of action is thought to involve the disruption of cell membranes and the induction of apoptosis.

Potential Therapeutic Applications

Due to its biological activities, undecylprodigiosin has potential therapeutic applications. It has been studied as a potential treatment for various types of cancer, including breast cancer, lung cancer, and leukemia. However, further research is needed to fully understand its mechanism of action and to assess its safety and efficacy in humans.

See Also

• Prodigiosin
• Streptomyces coelicolor
• Serratia marcescens

References

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