VE (nerve agent)

VE (nerve agent)

VE is a nerve agent that belongs to the V-series of nerve gases. It is a potent cholinergic agent that inhibits the breakdown of acetylcholine in the synapse, leading to a buildup of the neurotransmitter and overstimulation of the nervous system.

History

VE was first synthesized in the 1950s as part of a series of nerve agents developed by the Soviet Union. The V-series of nerve agents, which also includes VX and VR, were designed to be more potent and persistent than the G-series nerve agents such as sarin and soman.

Mechanism of Action

VE inhibits the enzyme acetylcholinesterase, which is responsible for breaking down acetylcholine in the synapse. This leads to a buildup of acetylcholine, causing overstimulation of the nervous system. Symptoms of VE poisoning include muscle spasms, respiratory failure, and seizures. In severe cases, exposure to VE can be fatal.

Treatment

Treatment for VE exposure involves the administration of atropine and pralidoxime, which help to counteract the effects of the nerve agent. Immediate medical attention is crucial, as the effects of VE can be rapid and severe.

See Also

• Chemical warfare
• Nerve gas
• Organophosphate poisoning