Valsartan/hydrochlorothiazide

From WikiMD's WELLNESSPEDIA

Chemical structure of Valsartan
Chemical structure of Hydrochlorothiazide

Valsartan/hydrochlorothiazide is a combination medication used to treat hypertension (high blood pressure). It combines two active ingredients: valsartan, an angiotensin II receptor antagonist, and hydrochlorothiazide, a thiazide diuretic.

Medical uses[edit]

Valsartan/hydrochlorothiazide is primarily prescribed for the management of hypertension. By lowering blood pressure, it helps to prevent strokes, heart attacks, and kidney problems. The combination of valsartan and hydrochlorothiazide works by relaxing blood vessels and reducing the amount of water and salt in the body.

Mechanism of action[edit]

Valsartan works by blocking the effects of angiotensin II, a substance in the body that causes blood vessels to tighten and narrow. By blocking this action, valsartan helps to relax and widen blood vessels, which lowers blood pressure.

Hydrochlorothiazide is a diuretic that helps prevent the body from absorbing too much salt, which can cause fluid retention. It increases the amount of urine passed, which helps to lower blood pressure.

Side effects[edit]

Common side effects of valsartan/hydrochlorothiazide include dizziness, lightheadedness, and dehydration. Serious side effects may include fainting, muscle weakness, and changes in the amount of urine. Patients are advised to report any severe side effects to their healthcare provider.

Contraindications[edit]

Valsartan/hydrochlorothiazide is contraindicated in patients with anuria or hypersensitivity to any component of the product. It should not be used during pregnancy as it can harm the fetus.

Interactions[edit]

This medication may interact with other drugs, including lithium, NSAIDs, and other blood pressure medications. Patients should inform their healthcare provider of all medications they are taking to avoid potential interactions.

Related pages[edit]

References[edit]

  • Leukotriene B4 hydroxylation pathway
    Leukotriene B4 hydroxylation pathway

Sponsored Health Resource

W8MD weight loss success

W8MD Weight Loss, Sleep & MedSpa

Looking for physician-supervised weight loss, semaglutide, tirzepatide, or GLP-1 receptor agonist options? W8MD helps eligible patients in New York City, Brooklyn, New Jersey, Connecticut, Pennsylvania, Delaware, and greater Philadelphia with medical weight loss, sleep medicine, and long-term maintenance support.

GLP-1 specials: Affordable GLP-1 injections NYC and Philadelphia starting from $29.99/week and up for semaglutide with insurance accepted for qualifying visits, and $45/week and up for tirzepatide with insurance accepted for qualifying visits. Self-pay options start from $59.99/week and up for semaglutide and $69.99/week and up for tirzepatide.

Book a W8MD appointment · View GLP-1 specials

Paid promotional message. Eligibility, pricing, insurance coverage, medication availability, and results vary. Medical evaluation required.

Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Retrieved from "https://wikimd.org/index.php?title=Valsartan/hydrochlorothiazide&oldid=6632953"